Phosphoramidon Disodium Salt ( Phosphoramidon disodium )

Catalog No. M18103 CAS No. 164204-38-0

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Product Name

Phosphoramidon Disodium Salt
Note

Research use only, not for human use.
Brief Description

Phosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool.
Description

Phosphoramidon disodium is a neutral endopeptidase (neprilysin) inhibitor. It blocks degradation of amyloid β peptides and endothelin converting enzyme (ECE).
Synonyms

Phosphoramidon disodium
Pathway

Others
Target

Other Targets
Recptor

metalloendopeptidase
Research Area

Others-Field
Indication

——

CAS Number

164204-38-0
Formula Weight

588.48
Molecular Formula

C23H34N3Na2O10P
Purity

98%
Solubility

H2O : ≥ 140 mg/mL; 238.31 mM
SMILES

[Na][Na].CC(C)C[C@H](NP(O)(=O)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
Chemical Name

sodium (oxido(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phosphoryl)-L-leucyl-L-tryptophanate

1. Komiyama T, et al. Biochem Biophys Res Commun. 1975, 65(1), 352-357.

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